Bayesian Sparsity-Path-Analysis of Genetic Association Signal using Generalized t Priors
نویسندگان
چکیده
منابع مشابه
Bayesian sparsity-path-analysis of genetic association signal using generalized t priors.
We explore the use of generalized t priors on regression coefficients to help understand the nature of association signal within "hit regions" of genome-wide association studies. The particular generalized t distribution we adopt is a Student distribution on the absolute value of its argument. For low degrees of freedom, we show that the generalized t exhibits "sparsity-prior" properties with s...
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ژورنال
عنوان ژورنال: Statistical Applications in Genetics and Molecular Biology
سال: 2012
ISSN: 1544-6115
DOI: 10.2202/1544-6115.1712